A Novel Tool for the Assessment of Pain: Validation in Low Back Pain

Scholz J, Mannion RJ, Hord DE, Griffin RS, Rawal B, et al
Background
Adequate pain assessment is critical for evaluating the efficacy of analgesic treatment in clinical practice and during the development of new therapies. Yet the currently used scores of global pain intensity fail to reflect the diversity of pain manifestations and the complexity of underlying [...]

Chronic Back Pain Is Associated with Decreased Prefrontal and Thalamic Gray Matter Density

Apkarian AV, Sosa Y, Sonty S, Levy RM, Harden RN, Parrish TB, Gitelman DR.
The role of the brain in chronic pain conditions remains speculative. We compared brain morphology of 26 chronic back pain (CBP) patients to matched control subjects, using magnetic resonance imaging brain scan data and automated analysis techniques. CBP patients were divided into [...]